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17 Biomimetic cardiovascular platforms for in vitro disease modeling and therapeutic validation

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  • 2019-12-25 18:36:40
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ContentslistsavailableatScienceDirectBiomaterialsjournalhomepage:www.elsevier.com/locate/biomaterialsBiomimeticcardiovascularplatformsforinvitrodiseasemodelingandtherapeuticvalidationRobertoPortillo-Laraa,b,AndrewR.Spencera,BrianW.Walkerc,EhsanShirzaeiSanic,NasimAnnabic,d,e,∗aDepartmentofChemicalEngineering,NortheasternUniversity,Boston,USAbTecnologicodeMonterrey,EscueladeIngenieríayCiencias,Zapopan,JAL,MexicocDepartmentofChemicalandBiomolecularEngineering,UniversityofCalifornia-LosAngeles,LosAngeles,CA90095,USAdCenterforMinimallyInvasiveTherapeutics(C-MIT),UniversityofCalifornia-LosAngeles,LosAngeles,CA,USAeHarvard-MITDivisionofHealthSciencesandTechnology,MassachusettsInstituteofTechnology,Cambridge,MA,USAABSTRACTBioengineeredtissueshavebecomeincreasinglymoresophisticatedowingtorecentadvancementsinthefieldsofbiomaterials,microfabrication,microfluidics,geneticengineering,andstemcellanddevelopmentalbiology.Inthecomingyears,theabilitytoengineerartificialconstructsthataccuratelymimictheco

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